Studies on the Regulation of Granulopoiesis
نویسنده
چکیده
I T IS NOW WELL ESTABLIShED that erythropoiesis is actively regulated in response to demand’ and evidence is accumulating that thrombopoiesis is ew2 A Priori reasoning and analogy suggest that granulopoiesis also is actively regulated but evidence to support this is scant. Reports by several groups of workers suggest that depletion of circulating neutrophils by means of leucapheresist or injection of antiserum4’5 leads to proliferation of marrow
منابع مشابه
A late-lineage murine neutrophil precursor population exhibits dynamic changes during demand-adapted granulopoiesis
Homeostasis of neutrophils-the blood cells that respond first to infection and tissue injury-is critical for the regulation of immune responses and regulated through granulopoiesis, a multi-stage process by which neutrophils differentiate from hematopoietic stem cells. Granulopoiesis is a highly dynamic process and altered in certain clinical conditions, such as pathologic and iatrogenic neutro...
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